Cancer Nanotechnology

Basic,Translational and Clinical Research

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  1. Original Paper

    Cisplatin-functionalized silica nanoparticles for cancer chemotherapy

    Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer including breast. Cisplatin was attached to silic...

    Chandrababu Rejeeth, Tapas C. Nag and Soundarapandian Kannan

    Cancer Nanotechnology 2013 4:43

    Published on: 20 July 2013

  2. Original Paper

    Intelligent system design for bionanorobots in drug delivery

    A nanorobot is defined as any smart structure which is capable of actuation, sensing, manipulation, intelligence, and swarm behavior at the nanoscale. In this study, we designed an intelligent system using fuz...

    Mark Fletcher, Mohammad Biglarbegian and Suresh Neethirajan

    Cancer Nanotechnology 2013 4:44

    Published on: 14 July 2013

  3. Original Paper

    Green synthesis of gold nanoparticles and their anticancer activity

    As the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. The secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanoma...

    Ravi Geetha, Thirunavukkarasu Ashokkumar, Selvaraj Tamilselvan, Kasivelu Govindaraju, Mohamed Sadiq and Ganesan Singaravelu

    Cancer Nanotechnology 2013 4:40

    Published on: 5 June 2013

  4. Original Paper

    Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

    Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. T...

    Chang Yang, Lun Ma, Xiaoju Zou, Guangya Xiang and Wei Chen

    Cancer Nanotechnology 2013 4:39

    Published on: 18 May 2013

  5. Original Paper

    Surface modification of cobalt oxide nanoparticles using phosphonomethyl iminodiacetic acid followed by folic acid: a biocompatible vehicle for targeted anticancer drug delivery

    The aim of our study was to prepare multifunctional, biocompatible nanoparticles for site-specific drug delivery. Hydrophilic nanoparticles with surface-adorned amine, carboxyl, or aldehyde groups, to be later...

    Sourav Chattopadhyay, Sandeep Kumar Dash, Totan Ghosh, Debasis Das, Panchanan Pramanik and Somenath Roy

    Cancer Nanotechnology 2013 4:42

    Published on: 26 June 2013

  6. Original Paper

    Active targeting of HER2-positive breast cancer cells by Herceptin-functionalized organically modified silica nanoparticles

    Normal micelle microemulsion method was utilized for fabrication of organically modified silica (ORMOSIL) nanoparticles. The void and dye-doped nanoparticles were synthesized in nonpolar core of two different ...

    Vahid Shirshahi, Fereshteh Shamsipour, Amir Hassan Zarnani, Javad Verdi and Reza Saber

    Cancer Nanotechnology 2013 4:35

    Published on: 27 March 2013

  7. Original Paper

    Antileukemic potential of PEGylated gold nanoparticle conjugated with protein toxin (NKCT1) isolated from Indian cobra (Naja kaouthia) venom

    Limited efficacy of current first-line treatment for leukemia calls attention for further development of efficient strategies. Recently, much attention has been given to nanoparticle-based drug delivery system...

    Tanmoy Bhowmik, Partha Pratim Saha, Anjan Dasgupta and Antony Gomes

    Cancer Nanotechnology 2013 4:36

    Published on: 10 April 2013

  8. Original Paper

    Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse

    As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood–brain barrier (BBB) represents...

    Mi-Ran Choi, Rizia Bardhan, Katie J. Stanton-Maxey, Sunil Badve, Harikrishna Nakshatri, Keith M. Stantz, Ning Cao, Naomi J. Halas and Susan E. Clare

    Cancer Nanotechnology 2012 3:29

    Published on: 20 July 2012

  9. Original Paper

    Development of in vitro gene delivery system using ORMOSIL nanoparticle: Analysis of p53 gene expression in cultured breast cancer cell (MCF-7)

    This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as an efficient in vitro gene delivery system in the recent years. Based on that prime objective, the present stud...

    Chandrababu Rejeeth, Soundarapandian Kannan and Krishnasamy Muthuchelian

    Cancer Nanotechnology 2012 3:30

    Published on: 29 July 2012

  10. Original Paper

    Apoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin

    Broad spectrum therapeutic potential of curcumin is usually hampered by its photodegradation and low bioavailability. Present investigation was designed with an objective to develop transferrin-mediated solid ...

    Rohit S. Mulik, Jukka Mönkkönen, Risto O. Juvonen, Kakasaheb R. Mahadik and Anant R. Paradkar

    Cancer Nanotechnology 2012 3:31

    Published on: 13 November 2012

  11. Original Paper

    PLGA nanoparticles loaded with etoposide and quercetin dihydrate individually: in vitro cell line study to ensure advantage of combination therapy

    PLGA nanoparticles, separately loaded with etoposide (ETN) and quercetin dihydrate (QDN), were prepared by adapting the solvent diffusion (nanoprecipitation) technique. The effect of formulation variables such...

    Smita Pimple, Arehalli S. Manjappa, Mukesh Ukawala and R. S. R. Murthy

    Cancer Nanotechnology 2012 3:27

    Published on: 9 May 2012

  12. Original Paper

    Aptamer-labeled PLGA nanoparticles for targeting cancer cells

    Cancer is one of the leading causes of death in most parts of the world and is a very serious cause of concern particularly in developing countries. In this work, we prepared and evaluated the aptamer-labeled ...

    Athulya Aravind, Saino Hanna Varghese, Srivani Veeranarayanan, Anila Mathew, Yutaka Nagaoka, Seiki Iwai, Takahiro Fukuda, Takashi Hasumura, Yasuhiko Yoshida, Toru Maekawa and D. Sakthi Kumar

    Cancer Nanotechnology 2012 3:24

    Published on: 19 January 2012

  13. Original Paper

    Clinical and pathological staging of the cancer at the nanoscale

    Clinical staging model at the nanoscale (CSMN) has been performed on adenocarcinoma of the colon from five patients ranging in age from 57 to 76 years based on determining their malignant size, estimating thei...

    Emad Y. Moawad

    Cancer Nanotechnology 2012 3:28

    Published on: 22 July 2012

  14. Original Paper

    Enhanced photodynamic efficacy and efficient delivery of Rose Bengal using nanostructured poly(amidoamine) dendrimers: potential application in photodynamic therapy of cancer

    Photodynamic therapy (PDT) is a promising treatment methodology whereby diseased cells and tissues are destroyed by reactive oxygen species (ROS) by using a combination of light and photosensitizers (PS). The ...

    Krishnamoorthy Karthikeyan, Anish Babu, Sang-Jae Kim, Ramachandran Murugesan and Kadarkaraithangam Jeyasubramanian

    Cancer Nanotechnology 2011 2:19

    Published on: 13 August 2011

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