Cancer Nanotechnology

Basic,Translational and Clinical Research

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  1. Research

    Cell localisation of gadolinium-based nanoparticles and related radiosensitising efficacy in glioblastoma cells

    Recently, the addition of nanoparticles (NPs) has been proposed as a new strategy to enhance the effect of radiotherapy particularly in the treatment of aggressive tumors such as glioblastoma. The physical pro...

    Lenka Štefančíková, Erika Porcel, Pierre Eustache, Sha Li, Daniela Salado, Sergio Marco, Jean-Luc Guerquin-Kern, Matthieu Réfrégiers, Olivier Tillement, François Lux and Sandrine Lacombe

    Cancer Nanotechnology 2014 5:6

    Published on: 10 October 2014

  2. Research

    Advantages of gadolinium based ultrasmall nanoparticles vs molecular gadolinium chelates for radiotherapy guided by MRI for glioma treatment

    AGuIX nanoparticles are formed of a polysiloxane network surrounded by gadolinium chelates. They present several characteristics. They are easy to produce, they present very small hydrodynamic diameters (<5 nm...

    Géraldine Le Duc, Stéphane Roux, Amandine Paruta-Tuarez, Sandrine Dufort, Elke Brauer, Arthur Marais, Charles Truillet, Lucie Sancey, Pascal Perriat, François Lux and Olivier Tillement

    Cancer Nanotechnology 2014 5:4

    Published on: 1 July 2014

  3. Research

    Effective cellular internalization of silica-coated CdSe quantum dots for high contrast cancer imaging and labelling applications

    The possibility of developing novel contrast imaging agents for cancer cellular labelling and fluorescence imaging applications were explored using silica-coated cadmium selenide (CdSe) quantum dots (QDs). The...

    Muthunayagam Vibin, Ramachandran Vinayakan, Annie John, Francis Boniface Fernandez and Annie Abraham

    Cancer Nanotechnology 2014 5:1

    Published on: 27 June 2014

  4. Original Paper

    Cisplatin-functionalized silica nanoparticles for cancer chemotherapy

    Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer including breast. Cisplatin was attached to silic...

    Chandrababu Rejeeth, Tapas C. Nag and Soundarapandian Kannan

    Cancer Nanotechnology 2013 4:43

    Published on: 20 July 2013

  5. Original Paper

    Intelligent system design for bionanorobots in drug delivery

    A nanorobot is defined as any smart structure which is capable of actuation, sensing, manipulation, intelligence, and swarm behavior at the nanoscale. In this study, we designed an intelligent system using fuz...

    Mark Fletcher, Mohammad Biglarbegian and Suresh Neethirajan

    Cancer Nanotechnology 2013 4:44

    Published on: 14 July 2013

  6. Original Paper

    Surface modification of cobalt oxide nanoparticles using phosphonomethyl iminodiacetic acid followed by folic acid: a biocompatible vehicle for targeted anticancer drug delivery

    The aim of our study was to prepare multifunctional, biocompatible nanoparticles for site-specific drug delivery. Hydrophilic nanoparticles with surface-adorned amine, carboxyl, or aldehyde groups, to be later...

    Sourav Chattopadhyay, Sandeep Kumar Dash, Totan Ghosh, Debasis Das, Panchanan Pramanik and Somenath Roy

    Cancer Nanotechnology 2013 4:42

    Published on: 26 June 2013

  7. Original Paper

    Green synthesis of gold nanoparticles and their anticancer activity

    As the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. The secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanoma...

    Ravi Geetha, Thirunavukkarasu Ashokkumar, Selvaraj Tamilselvan, Kasivelu Govindaraju, Mohamed Sadiq and Ganesan Singaravelu

    Cancer Nanotechnology 2013 4:40

    Published on: 5 June 2013

  8. Original Paper

    Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

    Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. T...

    Chang Yang, Lun Ma, Xiaoju Zou, Guangya Xiang and Wei Chen

    Cancer Nanotechnology 2013 4:39

    Published on: 18 May 2013

  9. Original Paper

    Antileukemic potential of PEGylated gold nanoparticle conjugated with protein toxin (NKCT1) isolated from Indian cobra (Naja kaouthia) venom

    Limited efficacy of current first-line treatment for leukemia calls attention for further development of efficient strategies. Recently, much attention has been given to nanoparticle-based drug delivery system...

    Tanmoy Bhowmik, Partha Pratim Saha, Anjan Dasgupta and Antony Gomes

    Cancer Nanotechnology 2013 4:36

    Published on: 10 April 2013

  10. Original Paper

    Active targeting of HER2-positive breast cancer cells by Herceptin-functionalized organically modified silica nanoparticles

    Normal micelle microemulsion method was utilized for fabrication of organically modified silica (ORMOSIL) nanoparticles. The void and dye-doped nanoparticles were synthesized in nonpolar core of two different ...

    Vahid Shirshahi, Fereshteh Shamsipour, Amir Hassan Zarnani, Javad Verdi and Reza Saber

    Cancer Nanotechnology 2013 4:35

    Published on: 27 March 2013

  11. Original Paper

    Development of in vitro gene delivery system using ORMOSIL nanoparticle: Analysis of p53 gene expression in cultured breast cancer cell (MCF-7)

    This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as an efficient in vitro gene delivery system in the recent years. Based on that prime objective, the present stud...

    Chandrababu Rejeeth, Soundarapandian Kannan and Krishnasamy Muthuchelian

    Cancer Nanotechnology 2012 3:30

    Published on: 29 July 2012

  12. Original Paper

    Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse

    As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood–brain barrier (BBB) represents...

    Mi-Ran Choi, Rizia Bardhan, Katie J. Stanton-Maxey, Sunil Badve, Harikrishna Nakshatri, Keith M. Stantz, Ning Cao, Naomi J. Halas and Susan E. Clare

    Cancer Nanotechnology 2012 3:29

    Published on: 20 July 2012

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